There now exists the possibility of gene therapy for cancers,
and many of the protocols currently approved for genetic
therapy are for patients with cancer. Several approaches are
being investigated, including virally directed enzyme prodrug
therapy, the use of transduced tumour infiltrating lymphocytes,
which produce toxic gene products, modifying tumour
immunogenicity by inserting genes, or the direct manipulation
of crucial oncogenes or tumour suppressor genes.
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